Useful Molecular Biology Bookmarks
Provided by Sidney Morris, Ph.D.


"This is a collection of databases and Web-based utilities that I have found useful for research and teaching purposes. Distinct from most such collections is the BASIC TOOLKIT section, which lists programs and Web sites that should meet the most common needs of many users. In some sections I have listed multiple sites for some types of analyses because not all Web utilities provide exactly the same functionality and flexibility of application. Based on my own interests, this collection is biased toward analysis of vertebrate sequences but links to other species can be tracked down from the resources listed here. This collection is by no means comprehensive, so if you can't find what you are looking for here, check the mega-collections of links under Section III. "



 I. GETTING STARTED: TUTORIALS AND GUIDES

II. BASIC TOOLKIT
A. RECOMMENDED FREE SOFTWARE
B. WEB-BASED TOOLS

III. MULTI-LINK LISTS OF DATABASES AND ANALYTICAL TOOLS


IV. SEARCH DATABASES

V. DATABASES
A. EST DATABASES
B. HUMAN DATABASES
C. MOUSE DATABASES
C.1. TRANSGENICS AND KNOCKOUTS
D. RAT DATABASES
E. YEAST DATABASES
F. OTHER SPECIES DATABASES
G. VECTOR DATABASES
H. MORE DATABASES-MULTIPLE CATEGORIES

VI. DNA ANALYSIS TOOLS
A. BASICS: SEQUENCE ASSEMBLY AND EDITING, FORMAT CONVERSION
B. RESTRICTION ANALYSIS
C. ALIGNMENTS
D. VISUALIZE ALIGNMENTS
E. TRANSCRIPTION FACTOR SITES
F. TRANSLATE DNA TO PROTEIN; CODON USAGE
G. DNA ANALYSIS TOOLS - UNSORTED

VII. RNA : GENE EXPRESSION AND SEQUENCE ANALYSIS
A. GENE EXPRESSION
B. ANALYZE SECONDARY STRUCTURE AND UTRs
C. SiRNA

VIII. DNA PRIMERS


IX. PROTEINS: ANALYSIS TOOLS AND DATABASES
A. DATABASES WITH SEARCH AND ANALYSIS TOOLS
B. SEQUENCE ALIGNMENTS
C. VISUALIZE PROTEIN ALIGNMENTS
D. STRUCTURE PREDICTION AND ANALYSIS
E. VISUALIZE PROTEIN STRUCTURE
F. 2-D PROTEIN GELS
G. PHYLOGENY
H. PROTEIN SITES - UNSORTED

X. PROTOCOLS, TIPS AND CALCULATIONS


XI. MOLECULAR BIOLOGY SOFTWARE (mostly free)

XII. BIOINFORMATICS TOOLS

XIII. MICROARRAYS
A. INTRO TO MICROARRAYS
B. MICROARRAY DATABASES
C. MICROARRAY LINK LISTS
D. SOFTWARE AND PROTOCOLS FOR MICROARRAY


I. GETTING STARTED: TUTORIALS AND GUIDES

 

BLAST tutorials
Tutorial: Finding homologs with BLAST
Primer on Finding Homologous Proteins or Genes
Tutorials Available at NCBI
Tutorials for NDB Structure Finder
NCBI Coffee Break: Contents
(SRS User's Manual)
Iterated profile searches with PSI-BLAST
BioScience Forum - Discuss Molecular Biology and Bioinformatics
EBI: Bioinformatics Educational Resource: Databases
EBI: Bioinformatics Tutorials
EBI: List of Bioinformatics Educational Resources

 

 

II. BASIC TOOLKIT

 

 

A. RECOMMENDED FREE SOFTWARE

 

BioEdit Sequence Alignment Editor for Windows 95/98/NT
About Chime and Where to get it
GeneDoc HomePage
Download ClustalX
Protein Explorer FrontDoor
EnzymeX - Restriction site analysis (Mac only)
Chimera: Interactive Molecular Visualization

 

 

B. WEB-BASED TOOLS

 

NCBI Site Map: Guide to NCBI Resources
Entrez cross-database search
BLAST at NCBI
Advanced BLAST at EMBNET
EBI Tools: Blast, Fasta, Sequence Analysis, Homology Searches, Sequence Translation, Protein Annotation, Genomes, Proteomes, Sequence Alignments
The Sequence Manipulation Suite
Webcutter 2.0 - Restriction Analysis
NEBcutter V2.0
READSEQ: Convert a Sequence to Different File Formats
SDSC Biology Workbench
Translate DNA to Protein--ExPASy
ExPASy - Tools
Protein Sequence Alignments at BCM
CUTTER: A tool to generate and analyze proteolytic fragments
PubCrawler: An update alert service
RefScoutŪ - Keeps track of your references
HighWire--Journal text search and email alert
BioMail: Automate custom PubMed searches
Human Genome Working Draft
The I.M.A.G.E. Collection of Vertebrate Genes
Mammalian Gene Collection
PubMed Bookshelf resources
BioQuery: Integrated Interface to BioMedical Databases.
 
 

III. MULTI-LINK LISTS OF DATABASES AND ANALYTICAL TOOLS

 

#1--The CMS-SDSC Molecular Biology Resource
#2--ExPASy Molecular Biology Server
#3-BCM Search Launcher Page
#4--Amos' WWW links page
#5--Mol Biol Database Collection--NAR 2003
Mol Biol Tools at Nucl. Acids. Res. (31 [13]) 2003
NAR Database Issue
HSLS: Molecular Biology & Genetics
Bioinformatics Supercomputer Utilities
LabVelocity : Tools
123 Genomics: genomics and bioinformatics resources
http://www.bioinformatics.vg/index.shtml
ABIM Online analysis tools
http://www.gene-regulation.com/pub/programs.html#matinspector
The Catalog of Databases
Research Tools
GenomeNet WWW server
Harvard Dept of MCB - Biology Links
All the Virology on the WWW
Virtual Library: Biosciences
Links to the Genetic World: 1
Swiss EMBnet node server
BioInfo Bank
Biomolecules Gallery

 

 

IV. SEARCH DATABASES

 

BLAST at NCBI
Advanced BLAST at EMBNET
Entrez Browser
BLAST Human Ensembl Genome Server
BLAST the Human Genome
NCBI Reference Sequence (RefSeq)
GOLD: Genomes OnLine Database Homepage
SWBIC - BLAST Filter
BLAST Mouse Ensembl Genome Server
BLAST Drosophila Ensembl Genome Server
SRS (Sequence Retrieval System) v6 Multi-database search/analyses
(SRS User's Manual)
The EMBL Nucleotide Sequence Database
GeneNest: gene indices as clusters of ESTs
MutationDiscovery.com
euGenes: Model Eukaryotic Organism Genes
PubGene
ORNL GenQuest Form
SDSC Biology Workbench
Search IMAGE Database of Human Genes
SWISS-PROT and TrEMBL
NCBI Taxonomy Browser
Animal Genome Size Database
EBI Databases
Bio Netbook
Human BLAT Search
WiGID - Wireless Genome Information Database
The Sanger Institute : Data Search

 

 

V. DATABASES

 

 

A. EST DATABASES

 

EBI's EST Links
dbEST NCBI (cDNA database)
The I.M.A.G.E. Collection of Vertebrate Genes
TIGR Gene Indices - The Institute for Genomic Research
Mammalian Gene Collection
stackPACK v2.2: cluster, align, analyze ESTs

 

 

B. HUMAN DATABASES

 

Ensembl Human Genome Server
BLAST the Human Genome
BODY MAP--human & mouse gene expression database
GeneCards: human genes, proteins and diseases (Weizmann)
Genome Catalog - human
GRLviewer: Human Gene Resource Locator
BCM Human Transcript Database Home Page
Human Genome Sequencing--BLAST and Progress Reports
The Genome Database
Human Genome Browser Gateway
HUNT: Human Full Length cDNA Database
LocusLink: An Integrated Information Site for Human Genes
NCBI Human Genome Guide: External Links
OMIM Home Page -- Online Mendelian Inheritance in Man
TIGR Human Gene Index
UniGene-Human
UTR Extender for Human mRNAs
HGVbase - Human Genome Variation database
Genelynx: A portal to the human genome

 

 

C. MOUSE DATABASES

 

BODY MAP--human & mouse gene expression database
Ensembl Mouse Genome Server
Genome Catalog - mouse
Mouse Genome Browser Gateway
Mouse Genome Home Page--JAX
Mouse Genome Index v2.3 -Gene Expression Menu
Edinburgh Mouse Atlas Project Database
TIGR MOUSE Gene Index
RIKEN Mouse Encyclopedia Index
Unigene- Mouse
The Whole Mouse Catalog
 

C.1. TRANSGENICS AND KNOCKOUTS

 

TBASE-Mouse Knockouts
Cre transgenic database - published lines
List of Floxed Genes
Mouse knockouts--Skarnes Lab Gene Traps
http://mouseblast.informatics.jax.org/
Blast The Mouse Genome
Genelynx: A portal to the mouse genome

 

 

D. RAT DATABASES

 

RATMAP: The Rat Genome Database
TIGR Rat Gene Index
Unigene-Rat
BLAST Against Baylor Rat Sequences

 

 

E. YEAST DATABASES

Saccharomyces Genome Database
Webminer: Gene expression in yeast
Yeast Genome Deletion Project
Yeast Genome Catalog

F. OTHER SPECIES DATABASES

 

List of Genomes at NCBI
ARK Multiple Species Databases
WormBase (C. elegans)
C. elegans Gene Index at TIGR
Drosophila Gene Index at TIGR
FlyBase Drosophila Genome
Genome Channel
Mullti-species Gene Indices at TIGR
Zebrafish Blast Server
ARKdb-pig Public Database Browser
Parasite Consensus EST Databases
Retroviruses
Virtual Genetics Library for Plants, Animals, Bacteria
Genome Tools for Microbes
Ciona Genome Project
OMIA: Online Mendelian Inheritance in Animals
The Viral Reference Genomes
Microbiology Microbes Bacteria Information and Links
BLAST Against Baylor Bovine Sequences
BLAST Against Baylor Chimpanzee Sequences
Search for ORFs in bacterial genomes

 

 

G. VECTOR DATABASES

 

Screen DNA Sequence for Vector Sequences with VecScreen
VecScreen Database of Vectors
I.M.A.G.E. Consortium Vectors
Maps of common vectors
Redasoft ResearchNet - Cloning Vector Search Engine

 

 

H. MORE DATABASES - UNSORTED

 

Databases available at SRS
COG
Complete Genome Tracking Database
The I.M.A.G.E. Collection of Vertebrate Genes
Alliance for Cellular Signaling (AfCS)
KEGG Regulatory Pathways
OWL Protein Sequence Database
Phosphoprotein Database (PPDB)
Protein Data Bank (PDB) at RCSB
SAGE (Serial Analysis of Gene Expression)
SPAD : Signaling PAthway Database
Transfac databases (not free)
TreeBASE /Phylogeny Home Page
The WWW Virtual Library: Model Organisms
Proteome Analysis Database
Official REBASE Homepage
Protein-DNA Recognition Database

 

 

 

VI. DNA ANALYSIS TOOLS

 

 

A. BASICS: SEQUENCE ASSEMBLY AND EDITING; FORMAT CONVERSION

 

BCM Search Launcher: Sequence Utilities
READSEQ: Convert a Sequence to Different File Formats
Sequence: complement, reverse complement, reverse
CAP3 Sequence Assembly Program
CAP : Sequence Assembly Program
BLAST output to FASTA format
CloneIt Online - Simulated Cloning Utility
Screen DNA Sequence for Vector Sequences with VecScreen
RepeatMasker--Screen for repeats and low complexity DNA sequences
TAP - Transcript Assembly Program (EST-based)
Submit a Sequence to GenBank
pDRAW32 - DNA cloning, sequence analysis and plasmid/DNA plotting
Savvy (draw plasmid map in SVG format)

 

 

B. RESTRICTION ANALYSIS

Restriction Enzyme Site Mapper version 3
Webcutter 2.0 - Restriction Analysis
NEBcutter V2.0
WatCut: Digest your DNA online, and create new restriction sites with silent mutations
EnzymeX - Restriction site analysis (Mac only)
Official REBASE Homepage
In silico restriction digest of complete genomes

 

C. ALIGNMENTS

 

Pairwise Alignment of DNAs: Blast 2
Pairwise DNA Alignment Tool
SIM4 - cDNA and Genomic DNA Alignment
Multiple Sequence comparison tools
Gene2EST: BLAST and align genomic DNA with ESTs
BLAT: Search/Alignment Tool for Human Genome
CONSENSUS sequences in unaligned DNA and protein sequences
PipMaker and MultiPipMaker
QAlign (download)
SWBIC GraphAlign
Spidey -- mRNA to genomic alignment at NCBI
Wise2: Dna Block Aligner
VISTA Alignment Tools for Comparative Genomics
Alfresco: Comparative genome visualization tool
DOTLET: Dot matrix alignment
Dot matrix plot
CodonAlign
Pairwise alignment utililty
Clustalw: Multiple alignments
MAVID, for multiple genome alignments
The Gibbs Motif Sampler for DNA

 

 

D. VISUALIZE ALIGNMENTS

 

BOXSHADE 3.33 Alignment Viewer/Printer
CINEMA 2.1 sequence alignment editor
CINEMA 5 sequence alignment editor
MVIEW multiple alignment viewer
Drawseq - biosequence drawing tool
Vista Genome Browser

 

 

E. TRANSCRIPTION FACTOR SITES

 

Alibaba2 (uses Transfac 4.0)
SiteSeer (uses Transfac 6.0)
MatInspector V2.2 (uses Transfac 4.0)
PatSearch 1.1 for TF sites
PromoSer: The mammalian promoter service
PROSPECT: Yeast Promoter Inspection Tool
SIGSCAN: Transcription Factor DNA Scan (uses Transfac 2.5)
TESS: Scan for Transcription Factor Sites (uses Transfac 4.0)
TFSEARCH (uses Transfac 3.3)
DBTSS: Database of transcription start sites
Transcription Factor Site Scan
Classification of Transcription Factors (1999)
TRANSFAC - The Transcription Factor Database
Transcription Regulatory Regions Database (TRRD)
TRANSCompel--Composite Regulatory Sites
Gene Regulatory Sequence Analysis
PRESTA promoter database (PRomoter-EST association)
Eukaryotic Promoter Database
RSAT: Regulatory Sequence Analysis Tools
MATCH tools for transcription factor sites (uses Transfac 3.5)
Target Explorer
Protein-DNA Recognition Database
Genomatix: Gene2Promoter
ConsInspector: transcription factor binding site prediction (download)
FastM and ModelInspector (use Transfac 4.0)
CONSITE
DNA sequence utilities at Softberry

 

 

F. TRANSLATE DNA TO PROTEIN; CODON USAGE

 

Translate DNA to Protein--ExPASy
ORF Finder
GeneMark 2.4: Analyze DNA sequence
Transeq: Translate DNA to protein
DNA Sequence Translator
Codon Usage Database for Different Species
Backtranslate Protein to DNA
Reverse Translate a Protein
Create codon usage table from DNA sequence
Codon usage table analysis
Countcodon program
JavaScript DNA Translator 1.1

 

 

G. DNA ANALYSIS TOOLS - UNSORTED

 

Link list: Tools for sequence comparisons
Sequence Analysis wwwTools
fastDNAml (DNA phylogenetic trees)
Gene Identification
Genome Channel
Analyze Unknown DNA Sequence with NIX
NetGene2: Predict splice sites
spliceNest: Visualize splicing of genes from EST data
UTR Extender for Human mRNAs
PatSearch
Kangaroo pattern search
MEME: Discover motifs
stackPACK v2.2: cluster, align, analyze ESTs

 

 

 

VII. RNA : GENE EXPRESSION AND SEQUENCE ANALYSIS

 

 

A. GENE EXPRESSION

 

Gene Expression Omnibus Home
SAGE Genie
SAGEmap at NCBI
x Profiler at CGAP: Tissue Expression Profiles
DigiNorthern1: Virtual Northern of EST expression
DigiNorthern 2: Compare expression of 2 ESTs
GETMaps: Tissue-specific Transcript Mapping
123 Genomics - Gene Expression, Microarrays, DNA chips and Differential Displays
GeneHopper - Main page

 

 

B. ANALYZE SECONDARY STRUCTURE AND UTRs

 

Algorithms, thermodynamics and databases for RNA secondary structure.
paRNAss: Predict RNA Secondary Structure
Sfold - Software for Statistical Folding and Rational Design of Nucleic Acids
Folding utilities at Zuker Lab
Vienna RNA Secondary Structure Package
The RNA World Website
The RNA WebRing
Rnadraw Homepage
UTR Homepage
ProSplicer: splicing database
RnaViz: Visualize RNA Structure
RNAML: tools to exchange RNA info
Gutell Lab Comparative RNA Web Site

C. siRNA

siRNA Converter
siRNA Target Finder
siRNA Construct Builder
Imgenex : siRna tool
siRNA Designer

 

 

 

VIII. DNA PRIMERS

 

Primer3 Input (primer3_www.cgi v 0.2)
Web Primer: PCR and Sequencing
PDA -Primer Design Assistant
The Primer Generator
CODEHOP: design of degenerate primers
PCR Guide
GeneFisher - Interactive PCR Primer Design
NetPrimer: Primer analysis at Premier Biosoft
DoPrimer
Primer Selection (Text)
Oligo Calculator
Molecular Probe Data Base
ExonPrimer - Primer Design
PROBEmer: Primer design for target families
PrimerX
In silico experiments with complete bacterial genomes: PCR, AFLP-PCR, PFGE

 

 

IX. PROTEINS: ANALYSIS TOOLS AND DATABASES

 

 

A. DATABASES WITH SEARCH AND ANALYSIS TOOLS

 

Protein Data Bank (PDB) at RCSB
Protein Information Resource Home Page
Human Protein Reference Database
BRENDA - Enzyme Database
Search EC Enzyme Database
InterPro Protein Database
GeneQuiz - Homolog search
ParAlign and SWMMX
Pfam : Home page (St. Louis)
COG: Clusters of Orthologous Groups of proteins
DIP: Database of Interacting Proteins
OWL Protein Sequence Database
PALI: Phylogeny and ALIgnment of Homologous Protein Structures
Kinase Sequence Database Version 3.0
LigBase: database of aligned ligand binding sites
Molecule Pages - AfCS Gateway
Phosphoprotein Database (PPDB)
The ProDom protein domain database
PEDANT Protein Analysis Tools
Proteome Analysis in Multiple Species
Protein-Nucleic Acid Recognition Database
Protein Kinase Resource
ProtoMap: Classification of Proteins at SWISSPROT
SAWTED Server: Search for homologs
JAKs and STATs
Alerts of New Sequences at SWISS-PROT
Proteome
SBASE - a protein domain library
Pattern Search in Protein Databases
The Protein Mutant Resource
Human Mitochondrial Protein Database
Advanced BLAST at EMBNET
Receptome
BCM Search Launcher: General Protein Sequence/Pattern Searches

 

 

B. SEQUENCE ALIGNMENTS

 

Protein Sequence Alignments at BCM
SIM Alignment Tool - Protein Sequences
ClustalW Alignment with Dendrogram (at DeCypher)
Clustalw
ClustalX (download)
T-COFFEE Multi-sequence alignment
DCA: Divide-and-Conquer Multiple Sequence Alignment
ConSurf: Map Degrees of Sequence Conservation in Aligned Proteins
STRAP: refinement of huge multiple alignments
CONSENSUS sequences in unaligned DNA and protein sequences
POA -- Sequence Alignment
Multiple Sequence Analysis Menu
MEME - Introduction
DOTLET
SWBIC GraphAlign
PRALINE: iterative multiple alignment using secondary structure
Protein Hub
HOMSTRAD
HOMSTRAD/PLUS
FUGUE: sequence-structure homology recognition and alignment engine
JOY
ALIGN
Alignment App
Wise 2: Align protein w/ genomic DNA
The Gibbs Motif Sampler for Proteins
EMBL Blast Protein Sequence Retrieval Tool - Input Form
PipeAlign: new session
PeCoP: Search for Conserved Positions/Residues

 

 

C. VISUALIZE PROTEIN ALIGNMENTS

 

GeneDoc HomePage
BOXSHADE 3.33 Alignment Viewer/Printer
CINEMA: Interactive Multi-alignment Editor
Easy execution of ESPript 2.0 / ENDscript 1.0
MVIEW multiple alignment viewer
ModView
ConSurf: Map Degrees of Sequence Conservation in Aligned Proteins

 

 

D. STRUCTURE PREDICTION AND ANALYSIS

 

A Guide to Structure Prediction
ExPASy - Tools
PSIPRED: a protein structure prediction server
http://pbil.ibcp.fr/cgi-bin/npsa_automat.pl?page=/NPSA/npsa_server.html
BioCoRE: A Tool-Oriented Collaboratory for Structural Biology
ESyPred3D: Predict protein 3D structure
BCM Search Launcher: Protein Secondary Structure Prediction
3D-JIGSAW Protein Comparative Modelling Server
http://npsa-pbil.ibcp.fr/cgi-bin/npsa_automat.pl?page=/NPSAHLP/npsahlp_locsoft.html
Protein Secondary Structure Prediction at BCM
Prediction servers for DNA and Protein Sequences
Sequence Analysis wwwTools
Emotif: exploring the motif universe
PeptIdent: Identify proteins
Pfam : Home page (St. Louis)
STING - Sequence To and withIN Graphics
CDART: Conserved Domain Architecture Retrieval Tool
FUGUE: Align sequences against structures
FUGUE Profile Lib Search
GeneFIND Protein Family Identification System
GENO3D : AUTOMATIC MODELING OF PROTEINS THREE-DIMENSIONAL STRUCTURE
GRASS Browser: Graphical Representation and Analysis of Structure Server
HMMTOP transmembrane/topology prediction
HOMSTRAD: Homologous Structure Alignment Database
MOTIF: Searching Protein and Nucleic Acid Sequence Motifs
Multilink List for Protein Sequence Analysis
NNPREDICT
Predict mitochondrial targeting sequence with MITOP
Predicting Protein 3D structure
Compare and align 3D protein structures
PROSPECT (Protein Structure Prediction)
Protein Fold Prediction
PSORT WWW Server
SBASE Protein Domain Library
SignalP: Predicts Signal Peptides
SubLoc 1.0: Predict subcellular location
SWISS-MODEL Protein Modelling Server
TMHMM 2.0---transmembrane prediction
TMAP: Transmembrane Sequence Predictor
TraDES: A New Way to Explore Protein Conformational Space
Comparative Sequence Analysis by SMART (Simple Modular Architecture Research Tool)
Trees from Blocks
Mathematical Biology at the National Institute for Medical Research - NIMR
SBASE structure prediction
NCBI VAST Home Page
Home page of ANTHEPROT
ProtFun 2.1 Server

 

 

E. VISUALIZE PROTEIN STRUCTURE

 

Find and visualize structures at The Protein Data Bank
Protein Explorer FrontDoor
DeepView - Swiss PDB Viewer Home Page
Chimera: Interactive Molecular Visualization
Cn3D Home Page
Annotated list of modeling programs
BioEditor Structure Annotation Tool
List of FREE Modeling Software
Free Molecular Visualization Software
MOLMOL - MOLecule analysis and MOLecule display
Molpov 2
NIH "Molecules R Us" Structure Viewer
RasMol Home Page
Visual Molecular Dynamics--3D Graphics
World Index of Molecular Visualization Resources
Collaborative Molecular Visualization in ToolSpace
Database of Macromolecular Movements
Chime Square
WebMol by Dirk Walther (UCSF)
PDB to MultiGif Page
VRML File Creator for Chemical Structures
MolScript: The Official Web Site
Center for Molecular Modeling
Links to Modeling Software
Motif3D Input Page
Running MICE as an embedded applet - MICE
Protein Morpher
PyMOL Home Page
XdomView: Visualize protein domains and exon structure

 

 

F. 2-D PROTEIN GELS

 

Partial List of Web 2D Electrophoretic Gel Databases
ExPASy - SWISS-2DPAGE top page
2D PAGE Databases
NCI Catalog of 2D PAGE gel images found in Web databases
Compare Gel Images with Flicker at NCI

 

 

G. PHYLOGENY

 

PhyloBLAST
Phylogenetics and Evolution Menu
Large List of Phylogeny Programs
WebPhylip
PhyloDraw: a drawing tool for creating phylogenetic trees
Oxford University Evolutionary Biology Group - Software
ATV - a phylogenetic tree display tool
treealign
Weighbor (Weighted neighbor joining)
fastDNAml (DNA phylogenetic trees)
TreeView Phylogeny Software
SHOT - Shared Ortholog and Gene Order Tree Reconstruction Tool
[ RIO SERVER ]
AllAll (Alignment, MSA, Probable Ancestral Sequence)
ETH: CBRG

 

 

H. PROTEIN SITES - UNSORTED

 

BLIMPS (BLocks IMProved Searcher)
CUTTER: A tool to generate and analyze proteolytic fragments
Enzyme Nomenclature
Codon Usage Database for Different Species
PatSearch
Kangaroo pattern search
Superfamily: for sequence search and alignment
SWBIC - BLAST Filter
InterProScan
BIND - The Biomolecular Interaction Network Database
NetPhos 2.0: Predict phosphorylation sites

 

 

 

X. PROTOCOLS, TIPS AND CALCULATIONS

 

Lab Protocols- quick index
Lab. Protocol 1
bioProtocol
metazoa > your online protocol system
BIOVISA.NET -- Online Protocol, Journal and Forum Center for Life Science Researchers
Molecular Biology Protocols
Molecular Biology Shortcuts - Protocols
NWFSC Molecular Biology Protocols
Wash U Mol Biol Protocols
Technical Tips at BioMedNet
Methods: A Companion to Methods in Enzymology
Interactive Statistical Calculation Pages
NIST Chemistry WebBook
SciWeb - The Life Science Home Page
PCR optimization | molbiol.ru
Gel Electrophoresis Simulator
CentrifugeHelper Version 1.1
BIOVISA.NET -- Online Protocol, Journal and Forum Center for Life Science Researchers

 

 

XI. MOLECULAR BIOLOGY SOFTWARE (mostly free)

 

AiO - DNA/protein programs and oligo management
The BioCatalog of Software
Huge Database of Molecular Biology Software and Online Tools at Genamics
GeneDoc HomePage
BioEdit Sequence Alignment Editor for Windows 95/98/NT
EnzymeX - Restriction site analysis (Mac only)
Free Molecular Visualization Software
Protein Explorer FrontDoor
CodonAlign
Educational Software for Biotechnology
Free Software for Mac and PC
List of Software for molecular biology
Genotator
BOXIT - Database for Molecular Biology Laboratories ($)
JaMBW: Java Molecular Biology Directory
MOLMOL - MOLecule analysis and MOLecule display
PaperWorks paper organizer
PC Software for Molecular Modeling
pDRAW32 - DNA cloning, sequence analysis and plasmid/DNA plotting
PHYLIP Software for Phylogenetics
PhyloDraw: a drawing tool for creating phylogenetic trees
RasMol Home Page
SEQtools downloads
SeqVerter: Sequence Format Converter
SeqVu-DNA sequence software (Mac only)
The Sanger Institute : Software
Software from TIGR
Software for computational molecular biology
StuffIt Expander: Unzip zip, access StuffIt files, free
Sequence Analysis for Mac OS X
TreeView Phylogeny Software
TREE-PUZZLE 5.0
Visual Molecular Dynamics--3D Graphics
WU BLAST at Wash U.
Affordable biocomputing for everyone
Apollo User Guide
Apollo Genome Annotation Tool
Handy Online Utilities at JustBio
Uniblast
ClustalX (download)
Jmol: Molecule viewer
Tools at Penn State Bioinformatics Group
Software Tools - The Institute for Genomic Research
Sweet2: Saccharide structure utility
MatchMiner Home Page
Alfresco: Comparative genome visualization tool
Home page of ANTHEPROT
Biolinux: Genomics Software
Welcome
Software for kinetics
ACGT
GeneMine: Free at last!
DNATools
Librarian - create full featured virtual PDF library
linkage software list (page 1)
Molecular Evolutionary Genetics Analysis
DARWIN: Data analysis and retrieval of protein, nucleic acid
Artemis: genome viewer and annotation tool

 

 

XII. BIOINFORMATICS TOOLS

 

Search Bioinformatics Sites with BioinfoBot
Bioinform - The Global Bioinformatics News Service
CuraToolsTM - Home Page

 

 

XIII. MICROARRAYS

 

A. INTRO TO MICROARRAYS

Intro to Microarrays
Microarrays-Introductory Factsheet
DNA Microarray (Genome Chip) (by Leming Shi, PhD)
Microarrays, their application and the standardisation of their data
Papers on Microarray Data Analysis

B. MICROARRAY DATABASES

Microarray Database at EBI
Gene Expression Omnibus Home
PubGene Expression Data Analysis Tool
The Stanford Microarray Database
Gene Expression Atlas: Text Query

C. MICROARRAY LINK LISTS

GoMiner: interpret "omic" data
MatchMiner Home Page
microarrays.org - your public source for microarraying information, tools, and protocols
microarray
Microarray Links at UCLA
Web resources on Gene Expression and DNA Microarray Technologies
GRID IT: Resources for Microarray Research
Microarray Citation Electronic Library
MicroArray Explorer Tool for Data Mining

D. SOFTWARE AND PROTOCOLS FOR MICROARRAY

NIH - DAVID
longhorn array database
EBI Microarray Tools - Expression Profiler
SMD Microarray Resources : Software & Tools
Microarray software comparison
CAGED Cluster Analysis of Gene Expression Dynamics
BASE: BioArray Software Environment
GAAS: Gene Array Analyser Software
GenMAPP Microarray Software
Free Microarray Software from Mike Tyers
Statistical Analysis of Microarray Data
OligoPicker Homepage
Intelligent Systems and Bioinformatics Laboratory
GeneSifter.Net?? - Microarray Analysis Online
cDNA Array Protocols

 


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